Ocular Toxicity
JOINN's ophthalmology laboratory was established in 2012 in our Suzhou facility to provide comprehensive and GLP compliant study services for the development of innovative ocular drugs and new ocular devices. A professional scientific research team consisting of 35+ people with high caliber of technical skills and 500 m2 of ophthalmology laboratory has been established and equipped with world-class comprehensive ophthalmic equipments. It has provided non-clinical experimental services to over 100 clients, completed over 500 service contracts, and assisted clients to complete nearly 30 domestic and foreign IND submissions.
Retinal Pigment Degeneration: RCS Rat & RDS Mouse
Cataract
Glaucoma
Diabetic Retinitis
Optic Nerve Disease
Other Retinal Diseases
Dosing Techniques
Topical
- Conjunctival sac (eye drops, ointments, gels)/periorbital skin
- Subconjunctival injection/ anterior chamber injection/ intravitreal injection/ subretinal injection/ suprachoroidal injection/ retrobulbar injection
Systemic
- Oral/ gavage/ intramuscular/ intravenous injection
Services
Safety evaluation
Efficacy evaluation
Pharmacokinetics
Animal Model
Wet AMD
- Choroidal Neovascularization (CNV)
- VEGF Induced Vascular Leakage
Glaucoma
IOP
Keratoconjunctivitis Sicca (KCS)
Allergic Conjunctivitis
Corneal Wound Healing
Corneal Neovascularization
Corneal Graft Rejection
Corneal Epithelial/Endothelial Cell Dystrophy
Oxygen Induced Retinopathy (OIR)
Retinal Neovascularization
Retinal Degeneration
Diabetic Retinopathy
Uveitis
Cataract
Ocular Ischemia/Reperfusion
Optic Nerve Degeneration
Myopia
New Model Development